ANTI-MIGRATORY EFFECT OF VINFLUNINE IN ENDOTHELIAL AND GLIOBLASTOMA CELLS IS ASSOCIATED WITH CHANGES IN EB1 C-TERMINAL DETYROSINATED/TYROSINATED STATUS.

We previously showed that vinflunine, a microtubule-targeting drug of the Vinca-alkaloid family exerted its anti-angiogenic/anti-migratory activities through an increase in microtubule dynamics and an inhibition of microtubule targeting to adhesion sites.Such effect was associated with a reduction of EB1 comet length at microtubule (+) ends.In this

In this paper, we Rutin consider the state estimation problem for flexible joint manipulators that involve nonlinear characteristics in their stiffness.The two key ideas of our design are that (a) an accelerometer is used in order that the estimation error dynamics do not depend on nonlinearities at the link part of the manipulators and (b) the mod

Abstract Recent empirical work highlights the heterogeneity of social competitions such as political campaigns: proponents of some ideologies seek debate and Gastrointestinal - Antacid conversation, others create echo chambers.While symmetric and static network structure is typically used as a substrate to study such competitor dynamics, network st

This paper addresses the challenge of enhancing the presentation style of visual exhibitions within museum settings, where the traditional approach can be perceived as unengaging.The study focuses on improving the performance of the ORB algorithm, a feature detection and matching method.Specifically, we introduce a novel technique that incorporates